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Dopamine-Secreting Carotid Body Paraganglioma in a Patient With SDHB Mutation

A newly published case report illustrates the diagnostic and monitoring benefits of dopamine testing for patients who are suspected or at risk of having dopamine-secreting head and neck paragangliomas. Key Points Paragangliomas are rare neuroendocrine tumors that originate from neural crest cells. Hypersecretory paragangliomas, such as those that secrete dopamine, are rare and may go...

Pulmonary Metastatic Follicular Thyroid Carcinoma Without Intrathyroidal Primary Thyroid Cancer

The existence of pulmonary metastatic follicular thyroid carcinoma with the presence of a primary thyroid neoplasm is a rare phenomenon that should be differentiated from ectopic thyroid tissues and should be considered in the differential diagnosis. The presence of benign and malignant pulmonary thyroid tissue is a rare finding. Individuals with ectopic thyroid tissue can...

Severe Hyponatremia With Immune Checkpoint Inhibitor Therapy in Mulvihill–Smith Syndrome

This case study reports the first known case of ICI-induced hyponatremia due to syndrome of inappropriate antidiuretic hormone release in a patient with Mulvihill–Smith syndrome. Vigilant monitoring for hyponatremia is recommended for patients on immune checkpoint inhibitor therapy who are predisposed to malignancies. Key Points Immune checkpoint inhibitors (ICIs), administered for treating solid and liquid...

Hypoglycemia Unawareness in a Type 1 Diabetes Mellitus Patient on Insulin

This case study highlights the need for a multidisciplinary approach for patient-targeted management in severe refractory cases of hypoglycemia in individuals with type 1 diabetes mellitus on insulin therapy. Key Points Hypoglycemia is a common complication of insulin therapy that increases the risk of developing cognitive impairment, cardiovascular complications, and hypoglycemia unawareness. There are no...

Hypercalcemia Associated With Severe Dysphagia in a Parathyroid Adenoma Patient

This case report highlights the association between hypercalcemia-induced dysphagia and parathyroid adenoma. It demonstrates how endocrine and metabolic diseases can impact esophageal motility.       Key Points Hypercalcemia in patients with parathyroid adenoma often causes constipation, pancreatitis, anorexia, and other gastrointestinal complaints. However, it can occasionally be associated with the development of aphagia or dysphagia. In this...

Following Drop After COVID-19 Onset, Inappropriate Antibiotic Prescribing Is Up

Initial decrease seen in proportion with inappropriate prescription, followed by subsequent increase There was an initial decrease in inappropriate antibiotic prescriptions following onset of COVID-19, followed by an increase, according to a study published online April 22 in Clinical Infectious Diseases. Kao-Ping Chua, M.D., Ph.D., from the University of Michigan Medical School in Ann Arbor, and...

Social Determinants of Health Tied to Atherosclerotic CVD Risk

Authors say social determinants could increase prediction ability of risk tools, particularly for Black patients Both individual- and area-level social determinants of health (SDOH) are associated with atherosclerotic cardiovascular disease (ASCVD) risk, according to a study published online April 26 in JAMA Network Open. Mengying Xia, M.P.H., from Columbia University in New York City, and colleagues...

Osteoporosis Screening Rates Low for Asian American Medicare Beneficiaries

Among Asian American beneficiaries, rates higher for women, those with higher household income Rates of dual-energy X-ray absorptiometry (DXA) screening for osteoporosis are lower than expected for Asian American Medicare beneficiaries, according to a study published online March 9 in Skeletal Radiology. Soterios Gyftopoulos, M.D., from New York University Langone Health in New York City, and...

Healthy Lifestyle Can Overcome Genetic Predisposition to Premature Death

Optimal healthy lifestyles include never smoking, regular physical activity, adequate sleep duration, and a healthy diet Adherence to healthy lifestyles can largely overcome the genetic risk for a shorter lifespan, according to a study published online April 29 in BMJ Evidence Based Medicine. Zilong Bian, from the Zhejiang University School of Medicine in Hangzhou, China, and colleagues investigated...

Hematospermia in a Transgender Woman With Prostatic Endometrial Tissue

Transgender women on gender-affirming hormone therapy are at risk of developing atypical presentations such as hematospermia and endometrial tissue growth in the prostate. This case study describes the development of hematospermia in a transgender woman. Key Points Hematospermia is a rare and self-limited benign condition that can be idiopathic, iatrogenic, or inflammatory in origin. The...
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